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Liver and Environmental Xenobiotics by S.V.S. Rana (English) Paperback Book
AU $100.50
ApproximatelyC $89.10
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Item specifics
- Condition
- ISBN-13
- 9783662123874
- Book Title
- Liver and Environmental Xenobiotics
- ISBN
- 9783662123874
About this product
Product Information
The general populations are incidentally exposed to a wide variety of xenobiotics as a consequence of the pollution of the environment by industrial and agricultural chemicals. Xenobiotics entering the animal will undergo one or more of the following fate: (a) elimination unchanged, (b) metabolism by enzymes, (c) spontaneous chemical transformation and (d) remain unchanged in the body. The actions of xenobiotics on the body exhibit certain specificity depending upon the compound's chemical structure and reactivity. Since the processes of metabolism change these chemical properties ofaxenobiotic, bewildering number of reactions continue to pose new challenges to toxicologists and pharmacologists. It necessitates periodic and precise revision of the subject. This book contains invited contributions from learned colleagues that offer an excellent survey of and profound insight into the disposition and metabolism of a few environmentally and industrially significant xenobiotics. The topics range from an assessment of drug metabolising enzymes in the liver, DNA damage by reactive oxygen species generated by pesticides, role of NO in liver injury, hepatotrophicgrowth factor in liver regeneration, extracellular matrix in the liver, oncogene expression in liver injury, the hepatocarcinogenesis to oxidative stress and undifferentiated gene expression. Detailed analysis of the validity of liver function tests has been included. Last Chapter addresses the problem of apoptosis, which plays a key role in the signal transduction system of xenobiotics-induced liver injury. The reader should appreciate that overall exposure to this field is expanding at a rapid pace and selections had to be made.
Product Identifiers
Publisher
Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
ISBN-13
9783662123874
eBay Product ID (ePID)
208898635
Product Key Features
Number of Pages
235 Pages
Language
English
Publication Name
Liver and Environmental Xenobiotics
Publication Year
2014
Subject
Medicine
Type
Textbook
Format
Paperback
Dimensions
Item Height
235 mm
Item Weight
385 g
Item Width
155 mm
Additional Product Features
Editor
K. Taketa, S.V.S. Rana
Country/Region of Manufacture
Germany
Item description from the seller
Seller business information
VAT number: AU 82107909133, GB 293967539
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