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Liver and Environmental Xenobiotics by S.V.S. Rana (English) Paperback Book

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Last updated on Apr 27, 2025 08:44:00 EDTView all revisionsView all revisions

Item specifics

Condition
Brand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ...
ISBN-13
9783662123874
Book Title
Liver and Environmental Xenobiotics
ISBN
9783662123874

About this product

Product Information

The general populations are incidentally exposed to a wide variety of xenobiotics as a consequence of the pollution of the environment by industrial and agricultural chemicals. Xenobiotics entering the animal will undergo one or more of the following fate: (a) elimination unchanged, (b) metabolism by enzymes, (c) spontaneous chemical transformation and (d) remain unchanged in the body. The actions of xenobiotics on the body exhibit certain specificity depending upon the compound's chemical structure and reactivity. Since the processes of metabolism change these chemical properties ofaxenobiotic, bewildering number of reactions continue to pose new challenges to toxicologists and pharmacologists. It necessitates periodic and precise revision of the subject. This book contains invited contributions from learned colleagues that offer an excellent survey of and profound insight into the disposition and metabolism of a few environmentally and industrially significant xenobiotics. The topics range from an assessment of drug metabolising enzymes in the liver, DNA damage by reactive oxygen species generated by pesticides, role of NO in liver injury, hepatotrophicgrowth factor in liver regeneration, extracellular matrix in the liver, oncogene expression in liver injury, the hepatocarcinogenesis to oxidative stress and undifferentiated gene expression. Detailed analysis of the validity of liver function tests has been included. Last Chapter addresses the problem of apoptosis, which plays a key role in the signal transduction system of xenobiotics-induced liver injury. The reader should appreciate that overall exposure to this field is expanding at a rapid pace and selections had to be made.

Product Identifiers

Publisher
Springer-Verlag Berlin and Heidelberg Gmbh & Co. Kg
ISBN-13
9783662123874
eBay Product ID (ePID)
208898635

Product Key Features

Number of Pages
235 Pages
Language
English
Publication Name
Liver and Environmental Xenobiotics
Publication Year
2014
Subject
Medicine
Type
Textbook
Author
S.V.S. Rana, K. Taketa
Format
Paperback

Dimensions

Item Height
235 mm
Item Weight
385 g
Item Width
155 mm

Additional Product Features

Editor
K. Taketa, S.V.S. Rana
Country/Region of Manufacture
Germany

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VAT number: AU 82107909133, GB 293967539
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