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Gap Junction

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Item specifics

Condition
Very Good: A book that does not look new and has been read but is in excellent condition. No obvious ...
Book Title
Gap Junction-Mediated Intercellular Signalling in Health and Dis
ISBN
9780471982593
Subject Area
Science
Publication Name
Gap Junction-Mediated Intercellular Signalling in Health and Disease
Item Length
9.3 in
Publisher
Wiley & Sons, Incorporated, John
Subject
Life Sciences / Cell Biology, Life Sciences / Biochemistry
Series
Novartis Foundation Symposia Ser.
Publication Year
1999
Type
Textbook
Format
Hardcover
Language
English
Item Height
0.7 in
Author
Novartis Foundation Symposium Staff
Item Width
6.1 in
Item Weight
20.8 Oz
Number of Pages
296 Pages

About this product

Product Information

Gap junctions are key elements in communication between cells in multicellular organisms.  It is clear that their activity is essential for normal embryonic development and normal function in adult organs, although the individual roles of the proteins that form the channels (connexins) are not yet fully understood. The last few years have seen considerable progress in this field and exciting new issues concerning gap junctional intercellular communication are being raised. Perturbed gap junction activity is beginning to be linked to certain pathologies, e.g. mutations in the major connexin of the heart have been found in human patients suffering from visceroatrial heterotaxia syndrome and mutations in the gene encoding another connexin have been found in patients with Charcot-Marie-Tooth disease. This book is the first to highlight the recent progress in understanding gap junction structure and to discuss the specific roles of individual connexins. It features contributions from an interdisciplinary group of experts who review the role of gap junctions in the heart, the retina and lens, the auditory system, the reproductive system, and in cell proliferation and cancer. The book will appeal to people interested in cell and molecular biology, embryonic development, neurobiology, cardiology, gynaecology and oncology.

Product Identifiers

Publisher
Wiley & Sons, Incorporated, John
ISBN-10
0471982598
ISBN-13
9780471982593
eBay Product ID (ePID)
999550

Product Key Features

Author
Novartis Foundation Symposium Staff
Publication Name
Gap Junction-Mediated Intercellular Signalling in Health and Disease
Format
Hardcover
Language
English
Subject
Life Sciences / Cell Biology, Life Sciences / Biochemistry
Series
Novartis Foundation Symposia Ser.
Publication Year
1999
Type
Textbook
Subject Area
Science
Number of Pages
296 Pages

Dimensions

Item Length
9.3 in
Item Height
0.7 in
Item Width
6.1 in
Item Weight
20.8 Oz

Additional Product Features

LCCN
98-046843
Intended Audience
Scholarly & Professional
Series Volume Number
238
Lc Classification Number
Qh603.C4g355 1999
Volume Number
No. 219
Reviews
"....this book in my opinion, is necessary to keep abreast in this rapidly progressing field.....", , , Cell Biology International#
Table of Content
Molecular Biology of the Interactions Between Connexins (N. Kumar).Electron Cryo-Crystallography of a Recombinant Cardiac Gap Junction Channel (V. Unger, et al.).Trafficking Pathways Leading to the Formation of Gap Junctions (W. Evans, et al.).Interactions Between Growth Factors and Gap Junctional Communication in Developing Systems (A. Warner).Biological Functions of Connexin Genes Revealed by Human Genetic Defects, Dominant Negative Approaches and Targeted Deletions in the Mouse (K. Willecke, et al.).Connexins in the Lens: Are They to Blame in Diabetic Cataractogenesis? (J. Kistler, et al.).Neuronal Coupling in the Central Nervous System: Lessons from the Retina (D. Vaney).Gap Junctions and Connexin Expression in the Inner Ear (A. Forge, et al.).Gap Junction-Mediated Communication in the Developing and Adult Cerebral Cortex (B. Nadarajah & J. Parnavelas).The Role of the Gap Junction Protein Connexin32 in the Pathogenesis of X-linked Charcot-Marie-Tooth Disease (S. Scherer, et al.).Cardiovascular Disease (N. Severs).Misregulation of Connexin43 Gap Junction Channels and Congenital Heart Defects (C. Dasgupta, et al.).Gap Junctional Intercellular Communication in the Mouse Ovarian Follicle (D. Goodenough, et al.).Connexins in Tumour Suppression and Cancer Therapy (H. Yamasaki, et al.).Summary.Indexes.
Copyright Date
1999
Dewey Decimal
612.6/2
Dewey Edition
21
Illustrated
Yes

Item description from the seller

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