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Two Faces of Evil: Cancer and Neurodegeneration (Research and Perspectives in A

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Last updated on Jun 11, 2024 19:52:11 EDTView all revisionsView all revisions

Item specifics

Condition
Very Good: A book that does not look new and has been read but is in excellent condition. No obvious ...
Book Title
Two Faces of Evil: Cancer and Neurodegeneration (Research and Per
ISBN
9783642166013
Subject Area
Science, Medical
Publication Name
Two Faces of Evil : Cancer and Neurodegeneration
Item Length
9.3 in
Publisher
Springer Berlin / Heidelberg
Subject
Neurology, Life Sciences / Neuroscience, Life Sciences / Cell Biology, Oncology
Series
Research and Perspectives in Alzheimer's Disease Ser.
Publication Year
2011
Type
Textbook
Format
Hardcover
Language
English
Author
Yves Christen
Item Width
6.1 in
Item Weight
16.8 Oz
Number of Pages
Xiv, 166 Pages

About this product

Product Information

Homeostasis involves a delicate interplay between generative and degenerative processes to maintain a stable internal environment. In biological systems, equilibrium is established and controlled through a series of negative feedback mechanisms driven by a range of signal transduction processes. Failures in these complex communication pathways result in instability leading to disease. Cancer represents a state of imbalance caused by an excess of cell proliferation. In contrast, neurodegeneration is a consequence of excessive cell loss in the nervous system. Both of these disorders exhort profound tolls on humanity and they have been subject to a great deal of research designed to ameliorate this suffering. For the most part, the topics have been viewed as distinct and rarely do opportunities arise for transdisciplinary discussions among experts in both fields. However, cancer and neurodegeneration represent yin-yang counterpoints in the regulation of cell growth, and it is reasonable to hypothesize that key regulatory events mediated by oncogenes and tumor suppressor genes in cancer may also affect neurodegenerative processes

Product Identifiers

Publisher
Springer Berlin / Heidelberg
ISBN-10
3642166016
ISBN-13
9783642166013
eBay Product ID (ePID)
99677435

Product Key Features

Author
Yves Christen
Publication Name
Two Faces of Evil : Cancer and Neurodegeneration
Format
Hardcover
Language
English
Subject
Neurology, Life Sciences / Neuroscience, Life Sciences / Cell Biology, Oncology
Series
Research and Perspectives in Alzheimer's Disease Ser.
Publication Year
2011
Type
Textbook
Subject Area
Science, Medical
Number of Pages
Xiv, 166 Pages

Dimensions

Item Length
9.3 in
Item Width
6.1 in
Item Weight
16.8 Oz

Additional Product Features

Intended Audience
Scholarly & Professional
Number of Volumes
1 Vol.
Lc Classification Number
Rc321-580
Reviews
From the reviews: "The authors look at the etiology and molecular pathophysiology of several genes involved in cellular demise and cell proliferation. ... The book is going to be of interest to cell biologists primarily and anyone with an interest in cancer or neurodegeneration." (Joseph J. Grenier, Amazon.com, September, 2013)
Table of Content
Foreword.- Mariano Barbacid: Updating the mammalian cell cycle: the role of interphase cdks in tissue homeostasis and cancer.- Karl Herrup: The role of Cdk5 as a cell cycle suppressor in post-mitotic neurons.- Alfred Nordheim and Bernd Knöll: Actin-SRF signaling in the developing and mature murine brain.- Eric C. Griffith, Paul L. Greer, and Michael E. Greenberg: The E3 ubiquitin ligase Ube3A regulates synaptic function through the ubiquitination of Arc. - Thomas Curran: Targeting children's brain tumors: development of hedgehog pathway inhibitors for medulloblastoma.- Young-Goo Han and Arturo Alvarez-Buylla: Primary Cilia as a switch in brain development and cancer.- Freda D. Miller and David R. Kaplan: Nervous system aging, degeneration, and the p53 family.- Frédéric Checler, Julie Dunys, Raphaëlle Pardossi-Piquard and Cristine Alves da Costa: p53, a molecular bridge between Alzheimer's disease pathology and cancers'.- Robert B. Da rnell: RNA regulation in neurodegeneration and cancer.- Dengke Ma, Junjie U. Guo, Guo-li Ming, and Hongjun Song: Bridging environment and DNA: activity-induced epigenetic modification in the adult brain.- Harry T. Orr: Cell signaling and neurodegeneration: a link with cancer.- Kenneth S. Kosik, Pierre Neveu, and Sourav Banerjee: The miRNA system: Bifurcation Points of Cancer and Neurodegeneration.- Sathyanarayanan Puthanveettil and Eric Kandel: Molecular Mechanisms For The Initiation and Maintenance Of Long-Term Memory Storage.- Subject Index
Copyright Date
2011
Illustrated
Yes

Item description from the seller

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fine item, professional packaging with super-fast shipping. Very well done. RECOMENDED SELLER!!! Would definitely purchase from this seller again. Great selection of merchandise, great communication. Have shopped at their brick and mortar in Frederick for years back in the 1980's and they are consistently still providing high quality merchandise at excellent and fair market prices. Can't complement enough!
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This is an outstanding seller to deal with. Fair prices that are more than reasonable in this economy. The product is even better condition than described, a true value for my money. Packaged and shipped well shows seller has concern for the products he sells to arrive in excellent condition. The seller is friendly and communicates timely with his customers. All in all I highly recommend this seller and would do business again anytime. Thank you and be safe. Good luck to the future.
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