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Innovations for Next-Generation Antibody-Drug Conjugates - 9783030086275

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Item specifics

Condition
Brand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ...
Book Title
Innovations for Next-Generation Antibody-Drug Conjugates
ISBN
9783030086275
Publication Year
2019
Type
Textbook
Format
Paperback
Language
English
Publication Name
Innovations for Next-Generation Antibody-Drug Conjugates
Item Height
235mm
Author
Marc Damelin
Publisher
Springer Nature Switzerland A&G
Item Width
155mm
Subject
Medicine, Biology
Item Weight
563g
Number of Pages
357 Pages

About this product

Product Information

Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field's history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.

Product Identifiers

Publisher
Springer Nature Switzerland A&G
ISBN-13
9783030086275
eBay Product ID (ePID)
24046586544

Product Key Features

Author
Marc Damelin
Publication Name
Innovations for Next-Generation Antibody-Drug Conjugates
Format
Paperback
Language
English
Subject
Medicine, Biology
Publication Year
2019
Type
Textbook
Number of Pages
357 Pages

Dimensions

Item Height
235mm
Item Width
155mm
Item Weight
563g

Additional Product Features

Series Title
Cancer Drug Discovery and Development
Country/Region of Manufacture
Switzerland
Editor
Marc Damelin

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  • GB 976952259
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