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Ecto-ATPases - 9781461377290
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Located in: Aldershot, United Kingdom
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Item specifics
- Condition
- Book Title
- Ecto-ATPases
- ISBN
- 9781461377290
- Publication Year
- 2012
- Type
- Textbook
- Format
- Paperback
- Language
- English
- Publication Name
- Ecto-Atpases: Recent Progress on Structure and Function
- Item Height
- 254mm
- Publisher
- Springer-Verlag New York Inc.
- Item Width
- 178mm
- Subject
- Chemistry, Botany, Biology
- Item Weight
- 596g
- Number of Pages
- 294 Pages
About this product
Product Information
It has been known for almost 50 years that many cells carry enzymes that hydro- lyze extracellular ATP, and the term ecto-ATPase was used first by Engelhardt 40 years ago. But until the end of the 1970's, the idea of an ATPase with its ATP hydrolyzing site on the outside of the cell membrane was met with substantial skepticism since it was thought that ATP was strictly intracellular. Nevertheless, ecto-ATPase activity was dem- onstrated using a variety of intact cells. Most ecto-ATPase(s) exhibited three common 2 characteristics: 1) activation by either Ca + or Mg2+, 2) insensitivity to the commonly used inhibitors ofF-type, P-type, and V-type ATPases, and 3) ability to hydrolyze nucleo- side triphosphates and often nucleoside diphosphates as well. At the same time, the dominant ATPase activity in many plasma membrane preparations was shown to be dis- tinct from the ion-pump ATPases, but had similar enzymatic properties as the ecto-AT- Pase(s). Thus the term E-type ATPase activity has been proposed for ATPase activity exhibiting these characteristics, and it is assumed that all ecto-ATPases are E-type AT- Pases. The converse is not true, however, since soluble E-type ATPases were shown to ex- sist in plants, microorganisms, and the saliva of blood sucking insects. These enzymes could be easily purified, and exhibited very high specific activity.
Product Identifiers
Publisher
Springer-Verlag New York Inc.
ISBN-13
9781461377290
eBay Product ID (ePID)
148984863
Product Key Features
Publication Name
Ecto-Atpases: Recent Progress on Structure and Function
Format
Paperback
Language
English
Subject
Chemistry, Botany, Biology
Publication Year
2012
Type
Textbook
Number of Pages
294 Pages
Dimensions
Item Height
254mm
Item Width
178mm
Item Weight
596g
Additional Product Features
Country/Region of Manufacture
United States
Editor
Terence L. Kirley, Aileen F. Knowles, Liselotte Plesner
Item description from the seller
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eBay item number:314661943039
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