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Central Neurotransmitt
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- Buy It NowCentral Neurotransmitter Turnover by C.J. Pycock (English) Paperback Book
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Item specifics
- Condition
- ISBN-13
- 9781461597803
- Book Title
- Central Neurotransmitter Turnover
- ISBN
- 9781461597803
- Publication Year
- 2012
- Type
- Textbook
- Format
- Trade Paperback
- Language
- English
- Publication Name
- Central Neurotransmitter Turnover
- Item Length
- 8.5in
- Publisher
- Springer
- Item Width
- 5.5in
- Item Weight
- 9.7 Oz
- Number of Pages
- VII, 197 Pages
About this product
Product Information
The concept of chemical transmission in the central nervous system has taken some time to be generally accepted, but an increasing number of compounds are now being recognized as hav ing a transmitter role in the brain. The acetylcholine system was the first to be discovered in the periphery and its charac teristic features of storage of transmitter in vesicles in the nerve terminal, its electrically-evoked release and rapid extra neuronal breakdown were considered to be necessary criteria for any neurotransmitter candidate. The subsequent elucidation of the noradrenergic system made it apparent that rapid enzymatic breakdown was not essential for a released transmitter, and the possibility of high-affinity re-uptake processes became establ ished as an alternative means of terminating the synaptic actions of a transmitter. With the eventual acceptance of the amino acids as excitat ory or inhibitory transmitters, the requirement for a transmit ter to be present in a low concentration overall (although locally concentrated in specific terminals) also had to be discarded. This necessitated the additional concept of specif ic metabolic pools with different functions being located in different cells or within different regions of the same cell. Some localization of glutamate and aspartate remote from excit able membranes is clearly essential since their overall brain concentrations would be sufficient to maximally depolarize the majority of neurones in the brain. The concept of separate metabolic pools has been supported by stUdies on turnover rate (see Chapter 5).
Product Identifiers
Publisher
Springer
ISBN-10
1461597803
ISBN-13
9781461597803
eBay Product ID (ePID)
237713413
Product Key Features
Publication Name
Central Neurotransmitter Turnover
Format
Trade Paperback
Language
English
Publication Year
2012
Type
Textbook
Number of Pages
VII, 197 Pages
Dimensions
Item Length
8.5in
Item Width
5.5in
Item Weight
9.7 Oz
Additional Product Features
Number of Volumes
1 Vol.
Lc Classification Number
H1-99
Table of Content
List of Contents.- Section I Turnover of Central Neurotransmitters.- 1 The Turnover of Neurotransmitters in the Brain: An Introduction.- 2 The Turnover of Catecholamines.- 3 The Turnover of 5-Hydroxytryptamine.- 4 The Turnover of Acetylcholine.- 5 The Turnover of Transmitter Amino Acids,With Special Reference to GABA.- 6 The Turnover of Peptides.- Section II Application of Turnover Studies to Specific Problems.- Differences in Dopamine Metabolism in Rat Striatum andOlfactory Tubercle.- Changes in Central 5-Hydroxytryptamine Turnover inducedby Acute and Chronic Inhibition of the Re-uptake Process.- Tail Pinch Induced Gnawing: Voltammetric and BehaviouralEffects of Fenfluramine.- Analysis of CSF Amine Metabolites and Precursorsincluding Tryptophan, 5HIAA and HVA by HPLC using Fluorescence and Electrochemical Detection in Primates: Effects of Probenecid.- Species Differences in the Acetylation of [3H]Cholinein Cortical Slices.- The Effects of GABA Uptake Inhibitors including 2,4-Diaminobutyric Acid on GABA Metabolism in vivo.- Concomitant Determination of Endogenous Release of Dopamine, Noradrenaline, 5-Hydroxytryptamine and Thyrotrophin Releasing Hormone (TRH) from Rat Brain Slices and Synaptosomes.
Copyright Date
1981
Intended Audience
Scholarly & Professional
Illustrated
Yes
Genre
Non-Classifiable
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Ok so I ordered this item listed as having free shipping. It was listed at $43.54 with free shipping. Somehow I ended up being charged $65.52. Then after waiting 3 weeks and having absolutely no tracking information I spoke with the seller who agreed to send a replacment, but despite charging me extra money was unwilling to ship that replacment in a way that wouldn't take atleast 3 more weeks. Ultimately this was a complete waste of time and the seller is not one that I would recommend.
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This is not a coloring book!!!!! It’s just a book of black and white photos and even if colored over would look horrible! This book is a scam and I have received 2 items out of 3 I ordered and the third hasn’t even been shipped. Tried to message seller but only option given is to send the item number but no way to give reason for dissatisfaction with item! I would advise not ordering anything from this seller…
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