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Synergistic Interaction and Cell Responses to Environmental Factors, Paperbac...
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eBay item number:386544783327
Item specifics
- Condition
- ISBN
- 9781634834995
- Book Title
- Synergistic Interaction and Cell Responses to Environmental Factors
- Book Series
- Biochemistry Research Trends Ser.
- Publisher
- NOVA Science Publishers, Incorporated
- Item Length
- 10.2 in
- Publication Year
- 2015
- Format
- Trade Paperback
- Language
- English
- Genre
- Science
- Topic
- Life Sciences / Cell Biology, Life Sciences / Biochemistry, Radiation
- Item Weight
- 22.3 Oz
- Item Width
- 7.1 in
- Number of Pages
- 347 Pages
About this product
Product Information
For a quantitative description of variety cell responses to ionising radiation, a mathematical model is suggested. In contrast to the conventional point of view that the relative biological effectiveness (RBE) of densely ionising radiation is determined only by physical characteristics of radiation, this book presents extensive experimental data demonstrating the importance of cell recovery ability in the RBE manifestation. The most impressive data obtained was mostly for diploid mutant cells at the log-stage of growth, in which the RBE was close to unity. It was also shown that the recovery process itself was not damaged after exposure to high-LET radiation, as well as the enhanced RBE values due to the increased yield of irreversible radiation damage from which cells were incapable of recovering. A novel direction in the study of radioprotecting and radiosensitising action of chemical compounds is also discussed and confirmed in the book. A new conception for the mechanism of synergy is suggested, in accordance with the synergy due to the formation of additional effective damages resulting from the interaction of sublesions. These sublesions are supposed to be non-effective when each agent is applied separately. This concept led to the development of original mathematical models of synergy, which is reviewed by the authors. The model predicts a number of general rules of interaction, the condition under which the highest synergy can be achieved, its value, and the dependence of synergy on the intensity of agents applied. Validation of the model was also verified for various physical and chemical factors, biological objects and end points. The theory appears to be appropriate and the conclusions valid.
Product Identifiers
Publisher
NOVA Science Publishers, Incorporated
ISBN-10
1634834992
ISBN-13
9781634834995
eBay Product ID (ePID)
219635926
Product Key Features
Book Title
Synergistic Interaction and Cell Responses to Environmental Factors
Number of Pages
347 Pages
Language
English
Publication Year
2015
Topic
Life Sciences / Cell Biology, Life Sciences / Biochemistry, Radiation
Genre
Science
Book Series
Biochemistry Research Trends Ser.
Format
Trade Paperback
Dimensions
Item Weight
22.3 Oz
Item Length
10.2 in
Item Width
7.1 in
Additional Product Features
Dewey Edition
23
Dewey Decimal
612/.01448
Lc Classification Number
Qh652
Table of Content
For Complete Table of Contents, please visit our website at: https://www.novapublishers.com/catalog/product_info.php'products_id=55734
Copyright Date
2015
Item description from the seller
Seller assumes all responsibility for this listing.
eBay item number:386544783327
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