Picture 1 of 1
The Glutamate/GABA
Condition:
3 available
Price:
US $239.47
ApproximatelyC $329.02
- Buy It NowThe Glutamate/GABA-Glutamine Cycle: Amino Acid Neurotransmitter Homeostasis by A
Shipping:
Located in: Fairfield, Ohio, United States
Delivery:
Estimated between Wed, Jun 26 and Mon, Jul 8 to 43230
Returns:
Payments:
Shop with confidence
Seller information
- 98.3% positive feedback
Registered as a Business Seller
Seller assumes all responsibility for this listing.
eBay item number:395142193053
Item specifics
- Condition
- ISBN-13
- 9783319832081
- Type
- NA
- Publication Name
- NA
- ISBN
- 9783319832081
- Book Title
- Glutamate/Gaba-Glutamine Cycle : Amino Acid Neurotransmitter Homeostasis
- Book Series
- Advances in Neurobiology Ser.
- Item Length
- 9.3 in
- Publisher
- Springer International Publishing A&G
- Publication Year
- 2018
- Format
- Trade Paperback
- Language
- English
- Illustrator
- Yes
- Genre
- Science
- Topic
- Life Sciences / Neuroscience
- Item Width
- 6.1 in
- Item Weight
- 23 Oz
- Number of Pages
- X, 416 Pages
About this product
Product Information
Fundamental biochemical studies of basic brain metabolism focusing on the neuroactive amino acids glutamate and GABA combined with the seminal observation that one of the key enzymes, glutamine synthetase is localized in astroglial cells but not in neurons resulted in the formulation of the term "The Glutamate-Glutamine Cycle." In this cycle glutamate released from neurons is taken up by surrounding astrocytes, amidated by the action of glutamine synthetase to glutamine which can be transferred back to the neurons. The conversion of glutamate to glutamine is like a stealth technology, hiding the glutamate molecule which would be highly toxic to neurons due to its excitotoxic action. This series of reactions require the concerted and precise interaction of a number of enzymes and plasma membrane transporters, and this volume provides in-depth descriptions of these processes. Obviously such a series of complicated reactions may well be prone to malfunction and therefore neurological diseases are likely to be associated with such malfunction of the enzymes and transporters involved in the cycle. These aspects are also discussed in several chapters of the book. A number of leading experts in neuroscience including intermediary metabolism, enzymology and transporter physiology have contributed to this book which provides comprehensive discussions of these different aspects of the functional importance of the glutamate-glutamine cycle coupling homeostasis of glutamatergic, excitatory neurotransmission to basic aspects of brain energy metabolism. This book will be of particular importance for students as well as professionals interested in these fundamental processes involved in brain function and dysfunction.
Product Identifiers
Publisher
Springer International Publishing A&G
ISBN-10
3319832085
ISBN-13
9783319832081
eBay Product ID (ePID)
22038654645
Product Key Features
Book Title
Glutamate/Gaba-Glutamine Cycle : Amino Acid Neurotransmitter Homeostasis
Format
Trade Paperback
Language
English
Topic
Life Sciences / Neuroscience
Book Series
Advances in Neurobiology Ser.
Publication Year
2018
Illustrator
Yes
Genre
Science
Number of Pages
X, 416 Pages
Dimensions
Item Length
9.3 in
Item Width
6.1 in
Item Weight
23 Oz
Additional Product Features
Series Volume Number
13
Number of Volumes
1 Vol.
Lc Classification Number
Rc321-580
Table of Content
Introduction to the Glutamate-Glutamine cycle.- Glucose, lactate, β-hydroxybutyrate, acetate, GABA, and succinate as substrates for synthesis of glutamate and GABA in the glutamine-glutamate/GABA cycle.- Anaplerosis for glutamate synthesis in the neonate and in adulthood.- Enzyme complexes important for the glutamate-glutamine cycle.- BCAA metabolism and NH3 homeostasis.- Glutaminases Vesicular Glutamate Uptake.- The glutamine transporters and their role in the Glutamate/GABA-Glutamine Cycle.- Glutamine Metabolism in Gliomas.- Oligodendrocytes: development, physiology and glucose metabolism.- Dysregulation of glutamate cycling mediates methylmercury-induced neurotoxicity.- Astroglia, glutamatergic transmission and psychiatric diseases.- Glutamine Synthetase: Role in Neurological Disorders.- The Glutamate - Glutamine Cycle in Epilepsy.- Index.
Copyright Date
2016
Item description from the seller
Seller assumes all responsibility for this listing.
eBay item number:395142193053
Shipping and handling
Item location:
Fairfield, Ohio, United States
Ships to:
Afghanistan, Albania, Algeria, Andorra, Angola, Anguilla, Antigua and Barbuda, Argentina, Armenia, Aruba, Australia, Austria, Azerbaijan Republic, Bahamas, Bahrain, Bangladesh, Belgium, Belize, Benin, Bermuda, Bhutan, Bolivia, Bosnia and Herzegovina, Botswana, Brazil, British Virgin Islands, Brunei Darussalam, Bulgaria, Burkina Faso, Burundi, Cambodia, Cameroon, Canada, Cape Verde Islands, Cayman Islands, Central African Republic, Chad, Chile, China, Colombia, Comoros, Cook Islands, Costa Rica, Cyprus, Czech Republic, Côte d'Ivoire (Ivory Coast), Democratic Republic of the Congo, Denmark, Djibouti, Dominica, Dominican Republic, Ecuador, Egypt, El Salvador, Equatorial Guinea, Eritrea, Estonia, Ethiopia, Falkland Islands (Islas Malvinas), Fiji, Finland, France, Gabon Republic, Gambia, Georgia, Germany, Ghana, Gibraltar, Greece, Greenland, Grenada, Guatemala, Guernsey, Guinea, Guinea-Bissau, Guyana, Haiti, Honduras, Hong Kong, Hungary, Iceland, India, Indonesia, Iraq, Ireland, Israel, Italy, Jamaica, Japan, Jersey, Jordan, Kazakhstan, Kenya, Kiribati, Kuwait, Kyrgyzstan, Laos, Latvia, Lebanon, Lesotho, Liberia, Liechtenstein, Lithuania, Luxembourg, Macau, Macedonia, Madagascar, Malawi, Malaysia, Maldives, Mali, Malta, Mauritania, Mauritius, Mayotte, Mexico, Moldova, Monaco, Mongolia, Montenegro, Montserrat, Morocco, Mozambique, Namibia, Nauru, Nepal, Netherlands, Netherlands Antilles, New Zealand, Nicaragua, Niger, Nigeria, Niue, Norway, Oman, Pakistan, Paraguay, Peru, Philippines, Poland, Portugal, Qatar, Republic of Croatia, Republic of the Congo, Romania, Rwanda, Saint Helena, Saint Kitts-Nevis, Saint Lucia, Saint Pierre and Miquelon, Saint Vincent and the Grenadines, San Marino, Saudi Arabia, Senegal, Serbia, Seychelles, Sierra Leone, Singapore, Slovakia, Slovenia, Solomon Islands, Somalia, South Africa, South Korea, Spain, Sri Lanka, Suriname, Svalbard and Jan Mayen, Swaziland, Sweden, Switzerland, Taiwan, Tajikistan, Tanzania, Thailand, Togo, Tonga, Trinidad and Tobago, Tunisia, Turkey, Turkmenistan, Turks and Caicos Islands, Tuvalu, Uganda, United Arab Emirates, United Kingdom, Uruguay, Uzbekistan, Vanuatu, Vatican City State, Vietnam, Wallis and Futuna, Western Sahara, Worldwide, Yemen, Zambia, Zimbabwe
Excludes:
APO/FPO, Alaska/Hawaii, Barbados, Belarus, French Guiana, French Polynesia, Guadeloupe, Libya, Martinique, New Caledonia, Panama, Papua New Guinea, Reunion, Russian Federation, US Protectorates, Ukraine, Venezuela, Western Samoa
| Shipping and handling | Each additional item | To | Service | Delivery*See Delivery notes |
|---|---|---|---|---|
| Free shipping | Free | United States | Economy Shipping | Estimated between Wed, Jun 26 and Mon, Jul 8 to 43230 |
| Handling time |
|---|
| Will usually ship within 10 business days of receiving cleared payment. |
| Taxes |
|---|
| Taxes may be applicable at checkout. Learn moreLearn more about paying tax on eBay purchases |
Sales tax for an item #395142193053
Sales tax for an item #395142193053
Seller collects sales tax for items shipped to the following provinces:
| Province | Sales Tax Rate |
|---|
Return policy
| After receiving the item, contact seller within | Refund will be given as |
|---|---|
| 30 days after the buyer receives it | Money Back |
The buyer is responsible for return shipping costs.
Payment details
Payment methods
Seller feedback (1,024,709)
i***6 (139)- Feedback left by buyer.
Past 6 months
Verified purchase
Item as described, good price, well packaged, arrived slightly later than hoped (not in time for Christmas ) but the order was placed in a very busy shipping period. No issue with the seller’s speed of response and sending the item. Great seller!
l***a (3507)- Feedback left by buyer.
Past month
Verified purchase
Excellent seller. Timely shipping, safe packing, good communication, great price and as described. Thank you. A+++
i***k (17)- Feedback left by buyer.
Past month
Verified purchase
Great seller with great communication! Item arrived complete, as described and for a good price. There was a bit of an issue with tracking the order at one point (not the seller's fault), but seller was proactive in reaching out to the carrier and myself to get everything back on track. Arrived when expected.