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The Role of Toll-Like Receptor 4 in Infectious and Non Infectious Inflammation b

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Item specifics

Condition
Brand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See the ...
ISBN-13
9783030563219
Type
NA
Publication Name
NA
ISBN
9783030563219
Publication Year
2021
Format
Trade Paperback
Language
English
Book Title
Role of Toll-Like Receptor 4in Infectious and Non Infectious Inflammation
Author
Francesco Peri
Item Length
9.3in
Publisher
Springer International Publishing A&G
Genre
Science, Medical
Topic
Immunology, Microbiology, Life Sciences / Biology, Chemistry / Organic
Item Width
6.1in
Item Weight
10.4 Oz
Number of Pages
Xi, 174 Pages

About this product

Product Information

TLR4 is one of the most important innate immunity receptors, its function mainly consisting in the activation of inflammatory pathways in response to stimulation by Pathogen-Associated Molecular Patterns (PAMPs) and Damage Associated Molecular Pattern molecules (DAMPs). This volume critically reviews the different types of TLR4 activators and inhibitors, discusses the role of molecular aggregates in agonism/antagonism as well as the pivotal role of the CD14 receptor in the modulation of TLR4 signal and the molecular details and actors of the intracellular cascade. The book presents the role of TLR4 in several pathologies, such as sepsis and septic shock caused by receptor activation by gram-negative bacterial lipopolysaccharide (LPS), in neurodegenerative and neurological diseases such as Parkinson and Alzheimer's diseases, and Amyotrophic Lateral Sclerosis (ALS). It reviews the role of TLR4 in neural stem cell-mediated neurogenesis andneuroinflammation and in Human Induced Pluripotent Stem Cells and Cerebral Organoids and discusses the emerging role of micro-RNA (miRNA) regulation by TLR4.

Product Identifiers

Publisher
Springer International Publishing A&G
ISBN-10
3030563219
ISBN-13
9783030563219
eBay Product ID (ePID)
20057283936

Product Key Features

Book Title
Role of Toll-Like Receptor 4in Infectious and Non Infectious Inflammation
Author
Francesco Peri
Format
Trade Paperback
Language
English
Topic
Immunology, Microbiology, Life Sciences / Biology, Chemistry / Organic
Publication Year
2021
Genre
Science, Medical
Number of Pages
Xi, 174 Pages

Dimensions

Item Length
9.3in
Item Width
6.1in
Item Weight
10.4 Oz

Additional Product Features

Series Volume Number
87
Number of Volumes
1 Vol.
Lc Classification Number
Qd431-431.7
Table of Content
Chapter 1. Chemically synthesized TLR4 ligands, their immunological functions and potential as vaccine adjuvant.- Chapter 2. Intracellular TLR4 signaling.- Chapter 3. TLR4 Ligands: Single Molecules and Aggregates.- Chapter 4. CD14: not just chaperone, but a key-player in inflammation.- Chapter 5. Toll-Like Receptor 4 interactions with Neisseria.- Chapter 6. Toll-Like Receptor4 and Damage-Associated Molecular Patterns (DAMPS).- Chapter 7. TLR4 in neurodegenerative diseases: Alzheimer and Parkinson disease.- Chapter 8. TLR4-mediated Neuroinflammation in Human Induced Pluripotent Stem Cells and Cerebral Organoids.- Chapter 9. The role of TLR4 in neural stem cells-mediated neurogenesis and neuroinflammation.- Chapter 10. Toll-Like Receptor 4 and the world of microRNAs.- Chapter 11. Metabolic reprogramming of myeloid cells upon TLR4 stimulation.
Copyright Date
2021
Dewey Decimal
616.079
Series
Progress in Inflammation Research Ser.
Dewey Edition
23
Illustrated
Yes

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grandeagleretail

grandeagleretail

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